Morgan Stanley & Co. LLC
New York, New York 10036
Goldman, Sachs & Co.
200 West Street
New York, New York 10282
August 7, 2015
Securities and Exchange Commission
Division of Corporation Finance
100 F Street, N.E.
Washington, D.C. 20549
|Attn:||Jeffrey P. Riedler, Assistant Director|
|Re:||Global Blood Therapeutics, Inc.|
|Registration Statement on Form S-1|
|Registration File No. 333-205563|
Ladies and Gentlemen:
In accordance with Rule 461 under the Securities Act of 1933, as amended (the Act), we, as representatives of the several underwriters, hereby join in the request of Global Blood Therapeutics, Inc. (the Company) for acceleration of the effective date of the above-named Registration Statement so that it becomes effective at 4:00 P.M., Washington, D.C. time, on August 11, 2015, or as soon thereafter as practicable, or at such other time as the Company or its outside counsel, Goodwin Procter LLP, requests by telephone that such Registration Statement be declared effective.
Pursuant to Rule 460 under the Act, we, as representatives of the several underwriters, wish to advise you that we have effected the following distribution of the Companys Preliminary Prospectus dated July 31, 2015:
|(i)||Dates of distribution: July 31, 2015 through the date hereof|
|(ii)||Number of prospective underwriters to which the preliminary prospectus was furnished: 4|
|(iii)||Number of prospectuses furnished to investors: approximately 2,190|
|(iv)||Number of prospectuses distributed to others, including the Company, the Companys counsel, independent accountants, and underwriters counsel: approximately 55|
We, the undersigned, as representatives of the several underwriters, have complied and will comply, and we have been informed by the participating underwriters that they have complied and will comply, with the requirements of Rule 15c2-8 under the Securities Exchange Act of 1934, as amended.
|Very truly yours,|
MORGAN STANLEY & CO. LLC
GOLDMAN, SACHS & CO.
Acting severally on behalf of themselves and the
|By:||MORGAN STANLEY & CO. LLC|
|By:||GOLDMAN, SACHS & CO.|
[Signature Page to Underwriters Acceleration Request]